Full thickness skin
ValidatedPrinted fibroblasts and keratinocytes, cultured in a differentiated interface into a dermis and epidermis with a forming basal membrane.
Test on human tissue, not on animals.
Human tissue models, printed with laser-based bioprinting, standardized and reproducible for your lab.
A spin-off of Goethe University Frankfurt.
Microscopy image of a bioprinted tissue model
Bioprinted full thickness skin model, fluorescence microscopy.
Used for
- Toxicology screening
- Efficacy testing
- Permeation and absorption
- Cosmetics and consumer safety
Most drugs that work in animals fail in people.
About 60% of drug candidates that clear animal studies still fail in human trials, and the reason is logic. Animals are not human, and animals have different anatomy, different immune systems and metabolisms.
We close the species gap instead of correcting for it. Our models are built with human cells, mimicking human physiology and giving human results.
Our bioprinter
Built specifically for this method: gentle enough for living human tissue, and precise enough for complex, multi-layered structures.
Nothing squeezes the cells
There is no nozzle and no extrusion pressure. Printed skin constructs have stayed viable in culture beyond forty days.
The cells do the rest
We create the ideal environment for each cell type, so the cells organize themselves into the right structure naturally.
Imaged while it is printed
An advanced microscope captures the printing process in real time, giving us in-line quality control, so every model is standardized and reproducible.
Nuvotis tissue portfolio
Each model arrives fully validated and standardized in a multiwell format. Different batch, same outcome.
Intestinal epithelium
AvailableA polarised epithelial barrier on a printed stromal compartment, including vascularisation, with tight junctions and a mucus film for apical and basolateral sampling.
Oral mucosa
AvailableNon keratinised buccal epithelium on a printed connective layer, for dental, orthodontic and oral care applications.
Breast tumor microenvironment
In developmentPatient-derived organoids encapsulated in a customized extracellular matrix, replicating the tumor microenvironment.
In development
Coming soonTell us which tissue would unblock your programme. We're already thinking about liver and BBB models next, and would love to talk about a co-development slot.